As Breplum says, using the 22.5 fittings would be hard with glued joints. Gotta get it right the first time.
If you have enough vertical distance, you could maybe use an offset closet flange. That gets you 1.5 inches in whatever direction you want. The Oatey and Sioux Chief units are good, and not likely to clog.
If you had a 4x3 closet bend, you could even use a 4-inch PushTite offset closet flange. But I suspect the available vertical would again prevent that from working for you.
Because you are not gluing these, you could use either the black or white one.