Comments, starting from the upstream end (primary bathroom):
- Keeping the building drain straight with no bends may look good on paper, but there's not a big upside. You could use a couple 22.5s or 45s to jog as required to make things easier or fix any issues.
- Kentucky has its own plumbing code which I have not perused. So I will give you both IPC and UPC based comments.
- For the primary WC vent take off, "rotated greater than 45 degrees" should be at least 45 degrees above horizontal, which is probably what you mean, it's just not clear.
- Upsizing that vent takeoff to 3" and bring 3" up to a cleanout in the wall would be a good practice at least (maybe required, cleanouts aren't my thing); the vent above the cleanout could 2" for UPC, 1.5" for IPC.
- Under the UPC, the vented WC can't wet vent any downstream fixtures, so you'd need to figure out alternate venting for the tub and the shower. Under the IPC, it's fine to use the vented WC for wet venting.
- The length of the lower lav drain is immaterial, even if you are using it for wet venting. What is limited is the trap arm, the distance from a fixture trap to the wet vent (the drain also serving as a vent), not the length of the wet vent itself.
- Both lavs will need dry vents, or for the IPC, AAVs.
- The shower trap arm needs to fall at most one trap diameter, or at most 2". So where its fixture drain joins the branch drain that is wet venting it, the combo would need to be horizontal, not rotated much at all.
- A wet vent like you plan can't carry the washing machine drainage. If you conceptually deleted the washing machine, then the two sinks could share a single stack that is a vent above, a drain below, and that drain could wet vent the WC. If you want to do that, you'd need to keep the washing machine drain (which requires its own vent, although that vent could join the stack at an elevation at least 6" above all the flood rims) separate and only just the WC drain downstream of where the lav drain stack joins it.
- You should check if your floor drain(s) require trap primers. Venting rules for floor drains are fairly forgiving, so I think what you show is fine.
Cheers, Wayne