It would probably be best for you to post before pictures of your proposed bathroom to give better description/drawings to fit your needs.
Most times I install piping for a toilet with a turn up for a vent immediately in the wall behind the toilet. From there I turn the piping whichever way it needs to go thereafter.
From there you can put wyes in the stack under the toilet to catch the other fixtures, just as long as you vent them individually. Otherwise you'll suck the traps dry when you flush the toilet.