WHen using tile, you may need to shift the pattern a bit from the middle...the goal should be to minimize small slivers of tile, boards, etc. at the edges. It looks much better to have nearly full tile all around. Then, if you are going to do something like have a boarder, it can get more complicated. With tile, you also have the option of selecting your grout line to take up a small amount. If the room is not rectangular, small slivers will look worse, as the taper will become more apparent. You may need to shift L-R, or End to End to achieve that. So, the answer is, it depends. Also, keep in mind that with tile, unless it is rectified, it can vary from piece-to-piece and box-to-box not only in size, but color. So, it's good to be drawing from multiple boxes when laying, to randomize things.