I would recommend you go no more than 8 days between regenerations. This will also allow you to get better salt efficiency.
You need to know the size of the Brine Line Flow (BLFC) control on your control. There is usually a sticker on the back of the unit that identifies the size installed. I note the instructions you posted (the link) speaks of a .25 gpm BLFC. The amount of water added during brine fill determines the amount of salt and the capacity setting you should use. The practical max capacity is 60K with a 2 cubic foot unit and to get that capacity you need to regenerate with 15 lbs of salt per cubic foot (30 lbs total). Each gallon of water added during brine fill dissolves 3 lbs of salt. so to get 30 lbs you need 10 gallons of water. If your BLFC is .25 gpm then you would need 40 minutes of brine fill.
Dre you on city or well water? Is there any iron in the water--if so did you factor it in the hardness reading--each ppm of iron adds 5 grains to get compensated hardness.
If you were to set it up for an average 8 day regeneration, using your figures, your desired capacity would be 22 x 225 x 8 ~= 40,000 grains. To get 40,000 grains you need 6 lbs salt per cubic foot or 12 lbs and that takes 4 gallons of brine fill water--so if your BLFC is .25 gpm that would be a setting of 16 minutes. I would set the safety factor to 15 percent with these settings along with an 8 day override.
Also the second BD should be the second backwash and a relatively short time--certainly not 40 minutes.
We can talk about specifics once you answer the questions above.