For the Vespin, the water supply can be 7" to the left of center.
With copper pipes, I can solder on a 90 el and move it over 2"
If worse comes to worse, you can always move it in the wall too.
The Vespin gives you the option of using the 10" Unifit adapter, that would make your 10.5" rough-in work.
The Vespin model would be CST764SG and then you would also need the 10" Unifit for it.
The rough-in is measured from the wall, not the floor mold.
The Drake will work with 10-7/8" and with the water at 3" left of center.
The Sanagloss, standard height version is CST744SG
Toto Vespin II CST474CEFG with SS114 Softclose seat.
This bowl was installed on a 13-1/2" rough-in using the 14" Unifit adapter.
The water shutoff can be as close as 5-1/2" to the left of center, unless it's higher off the floor, and then it can be even closer to center.
This shutoff had been replaced with a new 1/4 turn valve with brass nipple through the wall.
Installation was by James Love of Love Plumbing & Remodel 206-949-5683
In some of the older Seattle homes, the old toilets had been wall mounted tank toilets.
Those typically are 14" rough-in and need a flange repair to use standard closet bolt connections at the flange.
Everything is on the truck for that.
The Vespin comes with a standard 12" adapter or you can order a 10" or 14" adapter depending on your rough-in distance.