Pipes usually have an accumulation of crud on the inside. So, IMHO, there's no way to clear it totally from one location. If you did it from the highest location until clear, then only the internal local branches would need to be cleared, taking, probably less water after all.
Water companies periodically try to clear their main lines by opening up water hydrants. You need a lot of flow to actually clean the stuff out of the pipes in your internal piping. Unless you have a full-port valve, you'll probably never get it all out. The act of turning it on and off, when the water fills the pipes back up, it dislodges only a little bit of it.