Last year, I completed a complete electrical remodel where we used six inch Halo cans for general lighting. These were the choice of the electrician who overall did high quality work. We used white trim on a white ceiling. Whether or not you can live with he aesthetics of the 6" cans and trim is a decision you will have to make.
There is an energy efficiency downside of all the ceiling penetrations but there is some additional sealing you can do with an IC can, and I think that there may be some totally sealed cans (more expensive) available.
I chose to use non dimmable, standard A base BR30 CFL floodlights everywhere. They have an internal starter/ballast and do not require anything special in the can. After trying may brands of lamps in an single can before purchasing for the whole house, I selected the Home Depot brand N:vision soft white(2700K) 14w (65 watt equivalent) BR30. They are rebranded TCP 2R3014's. TCP is one of the top tier manufacturers. In my opinion these bulbs were the best choice overall with regard to color, cost, and rapid turn on time. I found that across bands, the same advertised color temperature could have different appearance and color rendition.
I have lost one lamp out of 65 with an early failure, after about one year. Who knows if the advertised five to seven year lifetimes will be achieved.
You will have to decide if the energy savings and environmental benefits of CFL's are worth the main performance drawback which is the non-instantaneous ramp up to full brightness. Actually, in a bathroom in the middle of the night it is a advantage ;-) There is an "instabrite" version of the lamp available from TCP but they are twice the cost of the standard. I have used a few in closets. I have no experience with the dimmable version of CFL's. Spring lamp CFL's do not work well in recessed lighting.
Whether or not to go with CFL's now or wait for affordable LED's is another call you will have to make. In my opinion, significant market pentration of the LED's was quite a way off, and I chose to take the benefits and drawbacks of CFL's now.