I concur, but it is harder to lay out that way, especially if going around corners. You'll get a lot of input at www.johnbridge.com where they specialize on tiling. Before laying tile, you may want to verify the joist and subflooring are up to the task. They have a deflection calculator and good industry guidelines from structural engineers and references available there as well. If you haven't checked them out, you may wish to.
Large format tile requires a very flat surface (level is nice but flat is essential) to produce a good output without huge extra skill and time inputs, especially if you are leaning towards small grout lines (which will only work if the tile are very consistent in size and thickness, flat, and square). Some tile are very consistent, some are quite flexible from their stated sizes and can vary from box to box and from tile to tile within the same box.