Not asthetically. You need room for the p-trap under the shower or tub - the choices are elevate the floor (looks tacky and ruins headroom), or chop a hole and run one under so gravity does its thing. It gets even more complicated depending on where the sewer line leaves the basement. Is it below the floor, or go out the sidewall? If it goes out the sidewall, you'll need a pump to get it out. If it is below the floor, depends on how far below, the pipes need to slope all the way to the sewer outside.