I would move the pocket door farther from the tub,
If you plan on tile, or a glass door with frame, you will want some solid wood near the edge of the tub.
If this is for the master, I would be thinking of two lavs, and keep the toilet on the same wall. Opposing fixtures in a room that is about six feet wide can be a little tight.
Going through concrete walls is not hard.
In a crawl like that, it's better to hang the pipes below the floor joists rather than drilling them.
Getting someone in to core the walls is easy.