I am not a plumber, but recently I had to run some new waste pipe to the cat iron stack. I used PVC for the whole run and then cut out a the hub in the cast iron with a rented cast iron cutter ( home depot ) then used no hub couplings with neoprene sleces to join the PVC to the cast iron.
You have to make sure that if you have cast iron above where you are cutting that it is well supported.
You say your's is all accessible, so I would use PVC from the stack to the toilet and get rid of the rest of the old piping.
-Ron




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