Normally, the toilet plumbing with it's larger pipe and fittings would be more important to line up, the other fixtures are easier to fit in after the fact.
The tub can be vented within 42" of the trap,
The toilets within 72"
Vents can be tied back together at 42" or higher
If you vent off of the horizontal line, most inspectors would like to see a wye fitting, not a santee.