i had the same size vanity, toilet, and tub-shower in 5000 sq.inches; you have 11,300 sq. inches. i had to expand my space to get a soaker tub and a shower in. We love it! Our soaker tub is 49"x49" and deep.
what is your question specifically? Post a little diagram, and i'll comment on layout. Show where your door is, where the drains are now, and where adjacent rooms are.