hj said:There is no "reaction" between them since the copper should not be wet. The problem would be movement due to expansion and contraction rather than a reaction or vibration. Anything that separates them, such as pipe wrap tape, will be beneficial, but the ideal thing would be to not have them touching in the first place, even if it is only by the smallest gap.
hj said:The water has to touch both metals in order to become the electrolyte. Water inside the pipe will only cause a reaction between dissimilar metals making up the piping system.