I agree with carlh on this often-debated subject. In my observation, the basic guts of faucets are not different. Most will include a plastic pop up with the box store version. Some brands, notably american standard, have some very different model names and numbers in the box store that are exclusive. Differences are in the trim and accessories. In the case of Delta, a 100-DST is the same no matter where you buy it. In the letters after the main model, are variations affecting spray hose, finish, etc. which can vary a lot.
The issue of qualitiy control for the store shipments is also hotly debated. We won't resolve that question in a short post like this!